Milia are benign, superficial keratinaceous cysts that present as fine, small white papules. This section discusses 6 medical conditions causing Milia en plaque. Dermatol Online J. Multiple eruptive milia is a condition characterized by the sudden development of crops of milia over the course of weeks to months. Indian J Dermatol. Volume 4: Central, Health: Amazon.sg: Books 2008;35(1):39-41. Br J Dermatol. Abstract: Milia en plaque (MEP) is an uncommon disorder characterized by an erythematous plaque containing numerous milia. Milia en plaque is an unusual presentation of milia. 2016;38(3):212-217. doi:10.1097/DAD.0000000000000445 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4760378, Rose RF, Merchant W, Goulden V. Retroauricular milia en plaque: a rare presentation of lupus erythematosus. Losada-Campa A(1), De La Torre-Fraga C, Cruces-Prado M. Author information: (1)Service of Dermatology, Hospital Provincial de Pontevedra, Spain. 2015;60(1):105. doi:10.4103/0019-5154.147871 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4318039. This patch or plaque often has a clear and defined border. These bumps can be confused with neonatal acne. google_ad_client: "ca-pub-9759235379140764", This section discusses 6 medical conditions causing Milia en plaque. Spots that can appear on the shaft of the penis, the labia, scrotum, or close to the mouth are called Fordyce spots. 1998 Sep;23(5):227-9. Milia en plaque. Noté /5. Milia en plaque (MEP) is an uncommon disorder characterized by an erythematous plaque containing numerous milia. 2007 Dec;157(6):1287-9. doi: 10.1111/j.1365-2133.2007.08223.x. 2007;157(6):1287-1289. Based on histopathological features, Terui and colleagues 45) suggest that milia en plaque may represent a hamartoma, similar to a tumor of follicular infundibulum and trichoadenoma. J Clin Oncol 2002; 20: 3030– 3032. The name "milia en plaque" is proposed for this unusual condition. Evidences show that primary milia originate in the hair follicle infundibulum, whereas the secondary forms may develop in various adnexal structures like sweat ducts, sebaceous glands, and hair follicle 19). Issues related to esthetics and differential diagnoses represent a concern to patients and a challenge for physicians. Milia en plaque is a rare variant of primary milia, characterized by numerous aggregated milia appearing on within an inflamed plaque up to several centimeters in diameter 1). Learn more about the potential causes and the treatment options here. Other topical agents, such as steroids4 and fluorouracil,5 have been implicated in causing milia. Milia en plaque is a rare, challenging-to-treat variant most often seen in the posterior auricular region. This is often the only symptom, though the area may also feel itchy. Here’s our process. Milia en plaque is a rare type of primary milia. The cause for milia en plaque is not fully understood. Achetez neuf ou d'occasion Methods . 5 Moisidis … The cause of milia en plaque is unknown. This article looks at different types of milia, their causes, and possible ways to get rid of them. Dermoscopy is helpful in diagnosing early, inconspicuous milia (Figure 3). in 1978 9). Tsoïtis G, Papadimitriou C, Asvesti C, Lefaki J, Lambroudi M, Hatzibougias J, Babi A. Dermatoses rétro-auriculaires à type de grains de milium en plaque [Retroauricular dermatitis of the “milia en plaque” type]. It is important that milia are correctly diagnosed. They usually disappear on their own within a few weeks. milia en plaque. When milia are associated with another condition or injury, that condition should be treated separately. Abstract. Two patients with an unusual cutaneous lesion consisting of milia on an erythematous edematous base are presented; the clinical and histologic features are described. Caption. Lesions are usually asymptomatic, but in a minority of cases a slight sensation of … Kouba and colleagues 43) suggest that alteration in the infundibulum of a hair follicle, which causes impaired keratinization and outlet obstruction, plays a role in de novo milia en plaque. In our case, perfumes were the only topical agents applied to the post- auricular areas. Br J Dermatol. Multiple eruptive milia tend to appear on the face, upper arms, and upper trunk. J Am Acad Dermatol. MEP is most common in middle-aged females. 3 Zimmerman GC, Keeling JH, Burris HA et al. Since then, less than 40 cases have been reported in literature till date Milia en plaque. Boehm and colleagues 41) proposed that damage to adnexal structures from underlying diseases results in the formation of milia. Milia en plaque is a rare, benign, localized, entity typically seen in adults after the third decade of life. Request PDF | Milia en plaque | Milia en plaque is an unusual variant of primary milia, possibly underreported. (PMID:668413) Abstract Citations; Related Articles; Data; BioEntities; External Links ' ' Hubler WR Jr, ' ' Rudolph AH, ' ' Kelleher RM Cutis [01 Jul 1978, 22(1):67-70] Type: Journal Article, Case Reports. Milia en plaque. Follicle-damaging dermatoses, tumours and external agents, can lead to this peculiar clinical pattern. Bilateral malar milia en plaque as primary presentation of discoid lupus erythematosus. Standard treatment for milia en plaque has not been established, but the condition can be treated with either medical or surgical modalities, including topical or oral retinoids, minocycline, photodynamic therapy, simple extraction, cryotherapy, ablative laser therapy, dermabrasion, electrodesiccation, or excision, with variable successes depending on the depth of the lesions 51), 52). Dermatol Surg. © 2004-2021 Healthline Media UK Ltd, Brighton, UK, a Red Ventures Company. Milia en plaque after cryotherapy has been described, supporting the theory of trauma-induced milia 42). Vajdi T, Lee WW, Paravar T. Penicillamine-associated cutis laxa and milia en plaque – case report and review of cutaneous changes associated with penicillamine. 1997 Jan;24(1):61-3. doi: 10.1111/j.1600-0560.1997.tb00788.x, Boehm I, Schupp G, Bauer R. Milia en plaque arising in discoid lupus erythematosus. Bilateral malar milia en plaque as primary presentation of discoid lupus erythematosus. Milia en plaque (MEP) is a rare form of milia. They form when skin flakes or keratin, a protein, become trapped under the skin. ), inflammatory skin diseases (particularly those involving the basement membrane zone, such as sub-epidermal bullous diseases), or the use of topical medication (topical corticosteroids, 5-fluorouracil) or systemic drugs (cyclosporine and benoxaprofen) 17). Milia en plaque. When milia are a concern, discuss treatment with a doctor. A total of 9 cases of milia en plaque have been reported in the pediatric literature to date. Am J Dermatopathol. 2 The etiology and pathogenesis of this rare variant are unknown, although associated cases of pseudoxanthoma elasticum and discoid lupus erythematosus have been reported. Wang AR, Bercovitch L. Congenital milia en plaque. In this paper, a case of milia en plaque is reported and a review of the literature is described. Causes of Milia en plaque: The following medical conditions are some of the possible causes of Milia en plaque. Volume 6: Central, Health: Amazon.com.au: Books They are often found in newborns but can affect people of any age. However, on occasion, a skin biopsy may be performed. Berk D.R., Bayliss S.J. BACKGROUND: Milia en plaque is a rarely described benign lesion characterized by milia within an erythematous base, usually located periauricularly. However, there has been no research on their effectiveness with milia. 2002;41(12):897-898. Primary milia occur in children and adults. Pediatr Dermatol. Spontaneous regression has also been reported 30). A simple discussion of these causes with additional information is below. Clin Exp Dermatol. We include products we think are useful for our readers. Disputing: 2, Mentioning: 25 - Milia en plaque is an unusual eruption typically occurring in the retroauricular area. 2. 2008; 59: 1050-1063. J Dermatolog Treat. There are likely to be other possible causes, so ask your doctor about your symptoms. It usually occurs behind the ears, on an eyelid, or on the cheeks or jaw area. Losada-Campa A, De La Torre-Fraga C, Cruces-Prado M. Milia en plaque. in 1978. Milia en plaque (MEP) is an unusual and extremely rare clinical variant of milia, characterized by multiple milia-like lesions overlying an erythematous edematous plaque with histologic findings consistent with milia. Br J Dermatol. Cryotherapy-induced milia en plaque: case report and literature review. Keohane SG, Beveridge GW, Benton EC, Cox NH. Lee SH, Kim SC. 1998;39(2 Pt 2):334-337. Background: Milia en plaque (MEP) is an unusual entity with a distinctive clinicohistologic appearance. J Am Acad Dermatol. Causes of Milia en plaque: The following medical conditions are some of the possible causes of Milia en plaque. Milia en plaque is a rare, challenging-to-treat variant most often seen in the posterior auricular region. Milia en plaque preferentially involves the head and neck area, including nose, forehead, cheeks, scalp, periauricular, periorbital, submandibular and supraclavicular regions (Figures 1 and 2) 46). Milia en plaque. It is … It is not always possible to prevent milia, for example, when they occur in newborns. Plaque-like erythema with milia: a noninfectious dermal mucinosis mimicking cryptococcal cellulitis in a renal transplant recipient. Toxic, epidermal, necrolysis-like reaction associated with docetaxel chemotherapy. Pediatr Dermatol. de Wet J, Jordaan HF, Visser WI. milia en plaque - this is an unpleasant disease. Milia are common in all ages and both sexes. 2008;59(6):1050-1063. J Dermatol. It should be noted, however, that recurrence is not uncommon 53). Dogra S, Kaur I, Handa S. Milia en plaque in a renal transplant patient: a rare presentation. A total of 9 cases of milia en plaque have been reported in the pediatric literature to date. Milia en plaque. To illustrate by a case report the clinical presentation and effect of dermabrasion on milia en plaque. The white bumps of neonatal acne vary in size, and are often surrounded by redness, while milia are generally uniform in size, with no redness. Dermatol Surg. While no specific remedy has been proven to remove milia quickly, these treatments are mostly low-risk. Milia are small, benign superficial keratin-filled cysts that result from the obstruction of a hair follicle or eccrine sweat ducts, measuring 1 to 4 mm in diameter 3). Although there have been a few cases described in children, we describe the first case in a newborn. Milia en Plaque. Milia are very common and may be seen at any age. Congenital Milia En Plaque Congenital Milia En Plaque Wang, Annie R.; Bercovitch, Lionel 2016-07-01 00:00:00 Milia en plaque is a rare, benign, localized, entity typically seen in adults after the third decade of life. Certain medications, specifically cyclosporine, may be involved in the development of milia en plaque 39). 1,2 Milia en plaque (MEP) is a rare form of primary milia characterized by the presence of milia on an erythematous-edematous or infiltrated erythematous plaque. Milia en plaque have a characteristic appearance. Perfume is unlikely to be the cause because involvement was unilateral, despite bilateral ap- plication. The exact pathomechanism and reason for postauricular localization is not yet understood. In this condition, multiple milia are clumped together in a broad, flat patch raised above the surrounding skin. Only one previous case of MEP has been treated with electrodesiccation. Footnote: Multiple yellowish cysts on an erythematous plaque and scattered open comedones in a malar distribution. Abstract Milia en plaque is a rare, benign, localized, entity typically seen in adults after the third decade of life. Although there have been a few cases described in children, we describe the first case in a newborn. Milia en plaque Milia en plaque Ergin, Şeniz; Başak, Pınar; Sari, Aliye 2000-01-01 00:00:00 Introduction Milia are quite common at all ages from infancy onwards. 1994 Jul;31(1):107. doi: 10.1016/s0190-9622(09)80235-1, van Lynden-van Nes AM, der Kinderen DJ. No optimal treatment is known. 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